Michael Booth
University College London,
United Kingdom
The Booth group has extensive experience in synthetic cell engineering, having developed light-activated DNA templates to tightly-regulate cell-free protein synthesis within synthetic cells (Booth 2016Sci. Adv. 10.1126/sciadv.1600056 and Hartmann 2023 JACS 10.1021/jacs.3c02350) and synthetic cells that can controllably communicate with neighbouring bacteria (Smith 2023 Nat. Chem. Biol. 10.1038/s41589-023-01374-7). Please visit our group website for more details about our research: www.boothlab.uk
Selected References
- Michael J. Booth et al. , Light-activated communication in synthetic tissues. Sci. Adv. 2, e1600056 (2016)
- Orthogonal Light-Activated DNA for Patterned Biocomputing within Synthetic Cells, Denis Hartmann, Razia Chowdhry, Jefferson M.Smith, and Michael J. Booth, Journal of the American Chemical Society 2023 145 (17), 9471-9480
- Smith, J.M., Hartmann, D. & Booth, M.J. Engineering cellular communication between light-activated synthetic cells and bacteria. Nat Chem Biol 19, 1138–1146 (2023)