Jure Derganc
University of Ljubljana,
Slovenia
After his BSc in Physics at the University of Ljubljana in 1997, Prof. Derganc completed his Ph.D. in Biophysics from the same university in 2003, with trainings at Boston University and at the Institute Curie. His research interests lie in both theoretical and experimental biophysics, with a primary focus o understanding the intricate dynamics of cells and cellular membranes, including cellular aggregates. Additionally, Prof. Derganc delves into the mechanisms of lipid membrane remodeling and engage in bottom-up synthetic biology of membranes, particularly giant lipid vesicles. He also investigates the biomedical applications of microfluidics, including single cell analysis and deformability cytometry, alongside investigating the biophysical applications of optical tweezers. His research portfolio also encompasses the study of large protein aggregates (protein particles) and their implications in clinical hearing tests.
Selected References
- Derganc, J., Zemljič-Jokhadar, Š., Majaron, B. and Kokot, G., 2023. Locally induced shockwaves for selective perforation of cargoloaded lipid vesicles with temporal and spatial control. RSC advances, 13(35), pp.24830-24834
- Kuzman, D., Klančnik, U., Grum, E. and Derganc, J., 2023. Real-Time Assessment of the Size Changes of Individual Sub-VisibleProtein Particles under Buffer Variations: A Microfluidic Study. Pharmaceuticals, 16(7), p.1002
- Pirc, Katja, et al., 2022. An oomycete NLP cytolysin forms transient small pores in lipid membranes. Science advances, eabj9406